The major histocompatibility complex class I (MHC-I) antigen presentation pathway is central to the adaptive immune response. In this process, intracellular proteins are degraded primarily by the ...
Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor ...
This study is led by Dr. Xingmei Qi and Dr. Sidong Xiong (Soochow University, China) and Dr. Gefei Chen (Karolinska Institutet, Sweden). In this study, the researchers develops an efficient protein ...
This is a preview. Log in through your library . Abstract Antigen-specific therapies hold promise for treating autoimmune diseases such as multiple sclerosis while avoiding the deleterious side ...
Researchers from Memorial Sloan Kettering Cancer Center and affiliated organizations presented data from a study that aimed to investigate the immunomodulatory functions of lysine-specific demethylase ...
Activation of certain memory B cells may be driving systemic lupus erythematosus incidence in individuals who had ...
The plasticity of macrophages depends on the spatial distribution, surrounding cell types, external microenvironment and extrinsic stimuli. This represents not only their capability to rapidly adapt, ...
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