Biochemists may soon find themselves reaching for palladium reagents—chemicals once thought to be exclusively used in organic synthesis—to couple small molecules, such as drugs, onto proteins.

Aryl halides*1) with a benzene ring directly bonded to a halogen atom are readily available and chemically stable, so they are used as a source of benzene rings in organic synthesis. For example, a ...

The importance of aryl sulfides in biologically active compounds has led chemists to develop methods to synthesize them from carbon-sulfur bond forming reactions. The conventional reaction, however, ...