Although much of bioprocessing still relies on large stainless-steel bioreactors, many biotherapy manufacturers are also turning to much smaller, single-use platforms, and that could be just the ...

Biopharmaceuticals are produced in living cells such as E. coli. But not all E. coli are alike. There are many different strains, and when combined with various expression plasmids needed for ...

Schematic of a typical bioreactor. Key components include the reactor tank, agitation system, feeding pump, thermal jacket, submerged aerator, and sensor probes for monitoring and maintaining optimal ...

Overexpression of an enzyme that degrades Eschericia coli mRNA leaves lots of room for the protected expression of exogenous proteins, and makes worries about background a thing of the past. You have ...