Researchers have uncovered how specific DNA rearrangements called inverted triplications contribute to the development of various genetic diseases. The study reveals that during DNA repair, segments ...

Soft tissue tumours and lesions characterized by USP6 gene rearrangements represent a heterogeneous group of neoplasms that include nodular fasciitis, aneurysmal bone cysts, cellular fibroma of tendon ...

This figure depicts how bridge recombinases have a dual targeting capability that enable these systems to insert new genetic material, delete unwanted regions, or flip existing DNA segments all in a ...

First clinical study reporting safety and outcomes of high dose oxaliplatin use in PIPAC for colorectal peritoneal carcinomatosis. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I.

Genomic disorders occur when there are changes or mutations in DNA that disrupt normal biological functions. These can lead to a range of health issues, including developmental delays and neurological ...

Did Changes in Drug Reimbursement After the Medicare Modernization Act Affect Chemotherapy Prescribing? Tumor specimens from patients with known independent primary tumors and metastatic lesions were ...

The paddy frog (Fejervarya multistriata) belonging to the family Dicroglossidae, is a species widely distributed in temperate and tropical Asia. In this study, the complete mitochondrial genome of F.

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...

Publication shows that OGM can resolve translocation partners involving MYC in multiple myeloma (MM) more effectively than current methods The release of compelling data in MM underscores the ...

Cancer’s most catastrophic DNA damage has long looked like a crime scene without a culprit, with chromosomes shattered and ...

A team of researchers has discovered that the memory of the immune system relies on characteristic epigenetic features and a specific 3D arrangement of the DNA in the nucleus of memory cells, allowing ...