Voltage-gated ion channels control electrical activity in nerve, muscle and many other cell types. The crystal structure of a bacterial voltage-gated channel reveals the astonishingly simple design of ...

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill ...

A new understanding of how drugs are taken in by cells could impact the way drugs are administered to patients. In an Aug. 30 study published in Nature that details structural changes of the Transient ...

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a 'ball-and-chain' channel-plugging mechanism. The findings boost the ...

Fifteen of the top-100 best-selling drugs target ion channels, and ion channel function is implicated in a large number of diseases as disparate as Alzheimer’s, epilepsy, heart disease, neuromuscular ...

Ion channels allow the movement of ions across cell membranes, and therefore fundamental physiological processes such as muscle contraction. In 1998, we saw for the first time what an ion channel ...