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  1. Monoclonal gammopathy of undetermined significance (MGUS)

    Dec 20, 2024 · Monoclonal gammopathy of undetermined significance (MGUS) is a condition in which an atypical protein is found in the blood. The protein is called monoclonal protein or M …

  2. M Protein (Myeloma Protein): Definition, Test, and Levels - WebMD

    Oct 12, 2024 · The M stands for monoclonal. Monoclonal means that all copies of the protein, in this case, an antibody or part of an antibody, are exactly the same.

  3. Monoclonal Gammopathy of Undetermined Significance (MGUS)

    Jun 19, 2025 · If blood and urine tests show M proteins, you’ll need regular blood and urine tests at least every six to 12 months. That way, your healthcare providers can watch for signs that …

  4. Monoclonal Protein: What It Is and What It Means

    Jul 19, 2025 · A monoclonal protein, also called an M-protein or paraprotein, is an abnormal antibody produced by a single (mono) group of plasma cells in the bone marrow. Its presence …

  5. Monoclonal Proteins (M Proteins) - Myeloma Center

    In healthy individuals, antibodies produced by plasma cells in the bone marrow help this process. When the body produces abnormal antibodies, they are called monoclonal proteins, or M …

  6. Monoclonal Gammopathies - Johns Hopkins Medicine

    These proteins are made from a small number of plasma cells in the bone marrow. The most common condition linked with these abnormal proteins is monoclonal gammopathy of …

  7. Monoclonal Gammopathy of Undetermined Significance | Moffitt

    Monoclonal gammopathy of undetermined significance (MGUS) occurs when plasma cells in the bone marrow produce an abnormal antibody known as monoclonal protein (M protein).

  8. Definition of monoclonal protein - NCI Dictionary of Cancer Terms

    An antibody found in unusually large amounts in the blood or urine of people with multiple myeloma and other types of plasma cell tumors. Also called M protein.

  9. M Protein (Myeloma Protein): Spike, Monoclonal, in Blood, More

    Feb 21, 2019 · What Does It Mean If You Have M Proteins in Your Blood? M proteins, or monoclonal proteins, are abnormal proteins. When they’re found in the blood or urine, they …

  10. Monoclonal Protein Study, Quantitative, Serum - Mayo Clinic ...

    Monoclonal proteins (M-proteins) are the marker of monoclonal gammopathies. An M-protein is defined by the presence of a monoclonal immunoglobulin that is expressed above the …