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jove.com
Video: Canonical Wnt Signaling Pathway
Video: Canonical Wnt Signaling Pathway
Dec 24, 2023
Wnt signaling pathway Functions
SOLVED: APC (adenomatous polyposis coli), a protein encoded by a tumor suppressor gene that is frequently inactivated in people with colorectal cancer, functions in the Wnt signaling pathway. This has inspired you to study Wnt signaling, and you would like to design a drug to treat people with colorectal cancer. What would be a good target (protein in the pathway) for this drug? Use the diagram to answer (keep in mind APC is not functional, and assume the drug only works in the colorectal epithe
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